For example, when considering patients hospitalized for alcohol-related rhythm disturbances, atrial fibrillation and atrial flutter appear to be most common arrhythmias.The first large prospective study regarding arrhythmias and alchohol was performed in Munich at Octoberfest in 2015.The prognosis of holiday heart syndrome (HHS) depends on the presence of any underlying heart disease.
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Ascherio et al. Pfeiffer D, Jurisch D, Neef M, Hagendorff A.
Ruigomez A, Johansson S, Wallander MA, Garcia Rodriguez LA.
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2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation. Engel TR, Luck JC. Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Effect of the 2014 atrial fibrillation guideline revisions on the proportion of patients recommended for oral anticoagulation.
Coined in 1978 the term is defined as "abnormal heart rhythms sometimes following excessive alcohol consumption; usually temporary".. Holiday heart syndrome can be the result of stress, dehydration, and drinking alcohol.
to describe a cardiac condition associated mainly with excessive alcohol consumption coupled with overeating and possibly a lack of sleep. Effect of the 2014 atrial fibrillation guideline revisions on the proportion of patients recommended for oral anticoagulation.
Antithrombotic Therapy Recommendations for Atrial Fibrillation
Hald EM, Enga KF, Lochen ML, et al. Table. 2001
2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society.
[Guideline] You JJ, Singer DE, Howard PA, et al. They may be characterized into two broad groups: direct effects on the myocardium and alcohol's effect on traditional risk factors for atrial fibrillation.With regard to direct effects on the atrial myocardium, alcohol causes a autonomic nervous system imbalance. This website also contains material copyrighted by 3rd parties.
Pathogenetic mechanisms of hypomagnesemia in alcoholic patients. Alcohol and atrial fibrillation: a sobering review.
Elisaf M, Merkouropoulos M, Tsianos EV, Siamopoulos KC. Elisaf M, Merkouropoulos M, Tsianos EV, Siamopoulos KC.
Alcohol intake and prognosis of atrial fibrillation.
encoded search term (What is the pathophysiology of holiday heart syndrome (HHS)?)
Predictors and prognosis of paroxysmal atrial fibrillation in general practice in the UK. /viewarticle/932998
Pathogenetic mechanisms of hypomagnesemia in alcoholic patients. Alcohol increases sympathetic nervous system (SNS) activity (and its related increased secretion of epinephrine and norepinephrine), with resultant effects including an increased release of calcium into the myocytes from the sarcoplasmic reticulum.Other direct effects on the myocardium are perhaps less well studied.
Uyarel H, Ozdol C, Gencer AM, Okmen E, Cam N. Acute alcohol intake and QT dispersion in healthy subjects.
Olesen JB, Lip GY, Hansen ML, et al.
In patients receiving warfarin, the INR should be determined at least weekly during initiation of antithrombotic therapy and at least monthly when anticoagulation (INR in range) is stable 2001
What exactly is it about alcohol that leads to holiday heart?
(See the Medscape Drugs and Diseases articles In the modern era, the term HHS has primarily been used to refer to acute cardiac rhythm disturbances related to acute alcohol consumption (ie, binge drinking), regardless of the underlying cardiac disease.Several mechanisms are theorized to be responsible for the arrhythmogenicity of alcohol. NVAF and history of TIA or stroke; age >75 years, if no history of unprovoked bleeding or intracranial hemorrhage; patients with dementia or occasional falls; however in patients with moderate to severe dementia or frequent falls, risk-benefit ratio is uncertain
Musher DM, Rueda AM, Kaka AS, Mapara SM.
Oral anticoagulants: Warfarin (INR 2.0-3.0) or dabigatran or rivaroxaban or apixaban based on assessment of risk of bleeding Musher DM, Rueda AM, Kaka AS, Mapara SM.
O'Brien EC, Kim S, Hess PL, et al. [Guideline] Culebras A, Messe SR, Chaturvedi S, Kase CS, Gronseth G. Summary of evidence-based guideline update: prevention of stroke in nonvalvular atrial fibrillation: report of the Guideline Development Subcommittee of the American Academy of Neurology.
No antithrombotic therapy The Holiday heart syndrome is a common cause of cardiac disease predominantly in the United States of America. Triflusal 600 mg/day plus moderate-intensity anticoagulation (INR 1.25–2.0) with acenocoumarol is likely more effective than acenocoumarol alone at the higher INR (2.0-3.0)
Apixaban, if at increased risk for gastrointestinal bleeding
[Guideline] Camm AJ, Lip GY, De Caterina R, et al, for the ESC Committee for Practice Guidelines (CPG).
Nguyen H, Romani A. Effects of low ethanol doses on heart rhythm in rabbits. Koskinen P, Kupari M, Leinonen H, Luomanmaki K. Alcohol and new onset atrial fibrillation: a case-control study of a current series. Eur Heart J.
Reza Shariatzadeh M, Huang JQ, Marrie TJ.
The "holiday heart": electrophysiologic studies of alcohol effects in alcoholics.
Yan J, Thomson JK, Zhao W, et al. Nguyen H, Romani A.
Clinically similar to idiopathic dilated cardiomyopathy, alcoholic cardiomyopathy is a major form of secondary dilated cardiomyopathy in the western world. [1] These patients consumed alcohol heavily and regularly; in addition, they t…
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