It remains a toxic substance in the system. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. This results in the accumulation of acetaldehyde in the blood that further leads to its high percentage in the blood. The syndrome is due to a deficit of aldehyde dehydrogenase and the gene for the Sjogren-Larsson syndrome gene is synonymous with this enzyme … An international team of researchers may have found one of the reasons why alcohol harms women more than men: women, it appears, are deficient in an enzyme that helps metabolize alcohol. It is a toxic compound that may lead to cell and tissue damage. The same goes true with alcohol as well. It stops the enzyme from binding its substrate thus prevents the processing and metabolism of alcohol which in turn increases the acetaldehyde in the blood.The overall effect of drinking alcohol is linked with the way it is metabolized by the body.Since the primary enzyme that is responsible for alcohol metabolism is alcohol dehydrogenase, which is lesser in women as compared to men, therefore, it is metabolized in their body at a slower rate as compared to men.Also, the body constitution is another important aspect that helps in knowing the metabolic effect of enzyme and alcohol metabolism. Our body processes food we intake by the action of various enzymes. It is one of the most important beverages that people prefer during parties, special occasions, festivals, etc. This eventually leads to acute hangover symptoms like nausea, vomiting, headache, etc.The person who is not able to produce alcohol catalyzing enzyme insufficient amount leads to the development of alcohol dehydrogenase deficiency symptoms commonly known as alcohol flush reaction.To measure the level of flush reaction the best method is to determine the level of acetaldehyde in the bloodstream.To improve the condition of deficiency of alcohol dehydrogenase there are some chemical drugs, that are meant to increase the level of enzyme thus help in processing alcohol at a faster rate.The pill contains different enzymes; oxidase, catalase and aldehyde dehydrogenase thus help the body to breakdown ethanol in the blood.Apart from the natural lowering of alcohol dehydrogenase, some alcohol dehydrogenase inhibitors compete for binding with its substrate.The compound that inhibits liver alcohol dehydrogenase from catalyzing the reaction is 3-substituted thiolane 1-oxides (methyl, n-butyl, n-hexyl, and phenyl). To improve the condition of deficiency of alcohol dehydrogenase there are some chemical drugs, that are meant to increase the level of enzyme thus help in processing alcohol at a faster rate. Thus, it plays a vital role in processing alcoholic compounds in the body.The one who consumes alcohol frequently. Women have more fat and lesser water than men have a slow metabolic rate thus more blood alcohol content than in men.According to the new study it has been found that around 600,000 people regardless of their age, gender, consumption who drank alcohol and analyzed their health over time are more prone to a higher rate of stroke, fatal aneurysms, heart failure, etc.According to recent studies, it has been found that taking light drinks (one to three drinks per week) reduces the rate of occurrence of cancer or death.Although the moderate consumption of alcohol does not harm the body, the regular consumption increases its demand thus making one the frequent drinker with a higher dose.Some of the common effects of alcohol on our body are discussed below.However, alcohol is metabolized in the liver, but its effect is displayed by its effect on the brain.Even one or two drinks can result in slurred speech, improper coordination, etc, taking it in too much amount can have more adverse effects.The studies revealed that alcohol dependencies are the major cause of Alzheimer’s disease and brain damage leading to dementia.Several factors help in analyzing the extent of the impact of drinking alcohol.

In the liver, alcohol dehydrogenase converts ethanol to harmless compounds, Carbon dioxide, and Water.But sometimes due to overconsumption of alcohol or due to some other disease these organs are not able to produce an adequate amount of enzyme, this leads to alcohol dehydrogenase deficiency.Now have you ever wondered what happens in the case when the body does not produce enough alcohol dehydrogenase?Generally, a person with a deficiency of alcohol dehydrogenase would not be able to breakdown ethanol to the simple product.The metabolism of alcohol begins with the breakdown of ethanol to acetaldehyde. Simply avoid alcohol, limit how much you drink or avoid certain types of alcoholic beverages.However, if you have a serious reaction or severe pain, see your doctor. Be aware, however, that labels might not list all ingredients.Mayo Clinic does not endorse companies or products.

This is caused by inherited (genetic) traits most often found in Asians.Other ingredients commonly found in alcoholic beverages, especially in beer or wine, can cause intolerance reactions.

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